Nitroglycerin does have tolerance over time which is why Imdur usually only lasts 12-16 hours in the blood for you to have an 8 hour Imdur free time (while sleeping usually). ISDUR4 has a two-position DIP-switch that enables the selection of configurations that apply to all channels. They are similar medicines that work in the same way, but the doses are different so you'll need to take the type that you're prescribed. Under the agreement, AstraZeneca will receive $190 million for the rights to Imdur. Isosorbide mononitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). október 2020 Skráðu lyfin Imdur 60 mg og 30 mg forðatöflur, allar pakkningastærðir eru nú ófáanleg hjá heildsala og óvíst er hvenær þau eru væntanleg aftur. What does Imdur look like?Angina can affect people in different ways and the symptoms may vary at different times. Macromatic’s ISD Series 4-channel intrinsically safe relays provide a safe and reliable method to control up to four loads with up to four input devices loca. By increasing nitric oxide production, Imdur helps lower blood pressure and reduce the risk of heart disease and other health complications. g. Trademarks, brands, logos, and copyrights are the property of their respective owners. Licence Number PA2129/001/001. 800. However, I have on numerous occasions taken Nitrostat when taking a much stronger dose of Isosorbide mononitrate. Liều lượng - cách dùng: 60mg, 1 lần/ngày vào buổi sáng. Davis PT Collection. A review. CONTRAINDICACIONES. MODIFIED RELEASE ISOSORBIDE MONONITRATE • Isosorbide mononitrate is widely used for the prophylactic treatment of angina pectoris. Optocoupler Relays. In smooth muscle, nitric oxide activates guanylate cyclase which increases guanosine 3’5’ monophosphate (cGMP) leading to dephosphorylation of myosin light chains and smooth muscle relaxation. ATC Code: C01D A. What Are Side Effects of Nitrolingual Pumpspray? Common side effects of. 1 out of 10 from a total of 67 ratings on Drugs. Learn about the side effects of Imdur (isosorbide mononitrate), from common to rare, for consumers and healthcare professionals. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Cardiovascular Implications of Erectile Dysfunction. 2Dosage Modificationsfor Adverse Reactions No dose reduction for treatmentis recommended. 5 mount template notes: 1. , LED indicator (s). 30 per tab er 24h for 90 tab er 24hs. Part #: ISDUR4 / RS Stock #: 71556973 Image may be a representation. Strength (s): 30MG [ AB], 60MG [ AB], 120MG [ AB] Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Imdur. 3 Dosing Considerationsالاقراص طويلة المفعول: 30 : 60 مجم بالفم مرة يومياً في الصباح. A total of 251 drugs are known to interact with nitroglycerin . Condition. vessels, making it easier for blood to flow through them and easier for the heart to pump. 0 Tablet pr) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. 2 out of 10 from a total of 19 reviews on Drugs. Buy Imdur® Isosorbide Mononitrate Online To eliminate the symptoms of malabsorption, the patient is prescribed a special diet enriched with animal proteins with a limited fat content (up to 30 g per day). It works by affecting the response to nerve impulses in certain parts of the body, like the heart. Our products are engineered and tested to be reliable, easy-to-use and high. Imdur 60mg Tablet 30'S. Isosorbide Dinitrate VS Isosorbide Mononitrate. Drugs. rochester. Amlodipine is in the drug class calcium channel blocking agents . 10. It serves as an exogenous source of nitric oxide which causes vascular smooth muscle relaxation and consequent dilation of peripheral arteries and veins. Oral medications. 35 59. It usually gets better after the first few weeks. 30 Inclusive of all taxes. Food can enhance the levels of metoprolol in your body. [2] DESCRIPTION. This medicine is available only with your doctor's. Common Imdur side effects may include: headache; or. It works by relaxing blood vessels, which decreases the amount of work the heart has to do. 36 110. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. This is probably a question best answered by your doctor or pharmacist. View Catalog Numbers. Sildenafil (Viagra) Use for Erectile Dysfunction. Eat light. You should take metoprolol at the same time each day, preferably with or immediately following meals. 58 65. It has a significant anti-anginal effect when taken once daily at a dose of 60 mg. Tadalafil, or generic Cialis, is most commonly used to treat erectile dysfunction (ED). After 2 weeks of placebo treatment. The full application process is handled on your behalf by NiceRx, providing you with a stress-free and affordable way to access your essential medication. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. INDICACIONES TERAPÉUTICAS. Inclusive of all taxes. This medication be. com. Get this at ₹142. The Innovation You Deserve. prevent angina attacks (chest pain). 19 per tab er 24h for 90 tab er 24hs at local U. 89 + free shipping and 2% Extra NeuCoins with. PDE5 is an enzyme in the walls of blood vessels. Dosage Considerations – Should be Given as Follows: Hypertension. 8 2. A. com. FARMACOCINÉTICA Y FARMACODINAMIA: Propiedades farmacocinéticas: IMDUR ® (5-mononitrato de isosorbida) se absorbe completamente y no sufre metabolismo de primer paso a través del hígado. Pharmacotherapeutic group: Vasodilators used in cardiovascular disease (organic nitrates). Imdur belongs to a class of drugs known as nitrates. Risk cannot be ruled out during pregnancy. The mechanism of hydrochlorothiazide-induced pancreatitis has been proposed to be due to direct ischemia, toxicity, and hypercalcemia (3). Imdur belongs to a group of medicines called nitrates. 238. Imdur is used in the treatment of Angina; Heart Failure; Angina Pectoris Prophylaxis and belongs to the drug class antianginal agents . Pain, tension and weakness during exertion, which. Take with fluid. Study with Quizlet and memorize flashcards containing terms like Which action is most important for the nurse to implement prior to the administration of the antiarrhythmic drug adenosine (Adenocard)? -Assess pupillary response to light. The end date for this SSSI has now been extended as the shortages are expected to continue until 31 May 2023. Male erectile dysfunction defined as “the inability to attain and/or maintain penile erection sufficient for satisfactory sexual performance” 1 is a common problem in the United States affecting between 10 and 30 million men. 20 per day depending upon your dose and where you purchase it. Imdur has an average rating of 6. Common interactions include oedema peripheral among females, and renal failure among males. Add to Cart. Lyfjanotendum er bent á að hringja á undan sér í apótek og kanna hvort lyfið sé fáanlegt í viðkomandi apóteki. It is very important that your doctor check your progress at regular visits. , M. isdur4 macromatic intrinsically safe relay 4. Initialt kortvarig pulserende hovedpine, rødme i ansigtet og svimmelhed, som ofte forsvinder ved fortsat behandling. No coffee/tea, smoking, nicorette gum or nicotine patches for 2 hours before. ISDUR4. e. Með vísan í 52. Potentielt alvorlige bivirkninger. 2. Angina Pectoris Prophylaxis. Macromatic Industrial Controls, Inc's ISDUR4 is an electromechanical relay 10 to 125vdc 102 to 132vac 5a spst( ()) din rail safety relay. Isordil may cause serious side effects including: lightheadedness, worsening chest pain, fast or slow heart rate, pounding heartbeats, fluttering in your chest, hives, difficulty breathing, and. Imdur has an average rating of 6. Other potential complications of portal hypertension include: jaundice, which causes yellowing of the skin. Part #: ISDUR4 / RS Stock #: 71556973. ISDN is available in immediate release (Ex: Isordil®) and extended release (Ex: DilatrateSR ®) forms. AB Hässle, Medical Department, Cardiovascular Research, Mölndal, Sweden. In case your problem is not Heart, then better to take 1/2 dose. Reported by a physician from United States on 2012-04-25 Patient: 75 year old female, weighing 48. February 29, 2016. 38% of reviewers reported a positive experience, while 38% reported a negative experience. What Imdur is and what it is used for. ₹ 47. Nitrofix SR 30 Tablet is used in the treatment of Angina (heart-related chest pain). Imdur is a vasodilator (that's good) but it also dilates ALL vessels including those to the brain (that's bad). Schwartz, M. Applies to: Imdur (isosorbide mononitrate) and Viagra (sildenafil) Using sildenafil together with isosorbide mononitrate is not recommended. As a result, the heart beats slower and decreases the blood pressure. shortness of breath. S. ISDUM4 has an 8-position DIP-switch for selecting configurations that apply independently to each channel. The phase IV clinical study analyzes which people take Imdur and have Chest pain. Isosorbide mononitrate will not treat an angina attack that has already started. The only possibly good news here is that. Grapefruit juice can increase the blood levels of atorvastatin. What is the difference or advantage of using isosorbide dinitrate over isosorbide mononitrate? It has high bioavailability and a longer half-life (4-6 hours) than ISDN. Watery, diarrhea stools. 64. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. 36 110. Isosorbide mononitrate reduces the workload of the heart by producing venous. Oral medications that include phosphodiesterase type 5 (PDE5) inhibitors are the first-line treatment for ED. Pharmacotherapeutic group: Vasodilators used in cardiovascular disease (organic nitrates). Viagra and Exercise – Generally speaking, combining Viagra and exercise is considered safe. Cart Total. 10. Katelyn Mehalic Isosorbide Mononitrate (Imdur) Nitrate. Other pharmacies. 2 4. Produces a vasodilator effect on the peripheral veins and. Sato's other meds? Select one: Lopid Praluent. 2. There are 7 disease interactions with Imdur (isosorbide mononitrate) which include: AMI. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). There are 209 drugs known to interact with Imdur (isosorbide mononitrate), along with 7 disease interactions, and 1 alcohol/food interaction. Image may be a representation. Browse sample topics. Toàn bộ viên hoặc nửa viên không được nhai hoặc nghiền và nên uống cùng với nửa ly nước. 238. Isosorbide relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). Description: Mechanism of Action: Isosorbide mononitrate is a vasodilator and the major active metabolite of isosorbide dinitrate. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Generic isosorbide mononitrate er is covered by most Medicare and insurance plans, but some pharmacy coupons or cash. Each tablet, for oral administration, contains either 30 mg, 60 mg or 120 mg of isosorbide mononitrate in an extended-release formulation. OTC, natural products, vitamins) and health problems. It has high. gr. The most common are sildenafil (Viagra) and tadalafil (Cialis. The risk of other side effects such as dizziness, lightheadedness, fainting, headache. Output: 5A SPST-NO. I felt very bad. Order Macromatic General Purpose Relay, 240VAC Coil Volts, Square, 0 Pin, (4) SPST-NO, ISDUR4 at Zoro. 2. 7474 | | sales@macromatic. Angina is a pain or uncomfortable feeling in the chest, often spreading to the arms or the neck and sometimes to the shoulders and back. C) Apply continuous cardiac monitoring. Generic Name: isosorbide mononitrate Pill with imprint IMDUR is White, Oval and has been identified as Imdur 30 mg. 29% of reviewers reported a positive effect, while 57% reported a negative. A radioactive isotope is injected through an IV and as a ‘tracer’ by going15. Pediatric (Off-label): 0. Nitrates and nitrites can cause methemoglobinemia, primarily in high-dose intravenous therapy or acute poisoning and in patients with NADH reductase deficiency. Page 1 of 4 Package leaflet: Information for the user Imdur® Tablets 60 mg isosorbide mononitrate Read all of this leaflet carefully before you start taking this medicine because it containsIf you are taking this medicine (isosorbide mononitrate extended-release tablets) for chest pain, it will not treat chest pain as it happens. Mfr. Imgur is the easiest way to discover and enjoy the magic of the Internet. Uses for Imdur ER. Configurations applied: Standard Logic (DIP Switch set to “STD”): When. The principal pharmacological action of isosorbide mononitrate, an active metabolite of isosorbide dinitrate, is relaxation of vascular smooth muscle, producing vasodilation of both arteries and veins with the latter effect predominating. Imdur (Isosorbide) falls in a class of drugs called nitrates. When the blood pressure is lowered, the amount of blood and. 60 mg, hjelpestoffer. Isosorbide dinitrate has an average rating of 4. com. Diagram right). 55% of reviewers reported a positive experience, while 35% reported a negative experience. Thuốc Imdur giúp cải thiện lưu lượng máu dưới nội tâm mạc. Isosorbide mononitrate belongs to the group of medicines called nitrates. Do đó, tác dụng tổng hợp của isosorbide. Select the shape (optional). Oct 6, 2009 • 6:40 AM. The price of 60 tablets of Ranexa (500 mg) is about $370, working out to approximately $12. A review. O. saberzt, bet jānorij, uzdzerot pusglāzi šķidruma. The administration ot isoso bide mono- nitrate extended-releas 120 mg (2 x 60 mg taileÈ 8very 24 hours tor 7Low blood pressure does not typically cause erectile dysfunction (ED). 0 Tablet pr) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. Isosorbide mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins. 0 2. 30 mg, 60 mg, 120 mg prolonged-release tablets are. In a single-blind study of 6 weeks' duration, 32 patients with stable angina pectoris, who had been receiving controlled-release, Durules, isosorbide-5-mononitrate (Imdur) 60 to 180 mg daily for at least 1 year, were assessed after abrupt withdrawal of the nitrate. Standard Modifications: None. IMDUR 60MG TABLET contains Isosorbide Mononitrate which beloqngs to the group of medicines called Nitrate vasodilators. In Stock: 1 Price Qty. Adult and Pediatric Dosage Forms and Strengths. Choose standard or inverse logic. Imdur 60 mg Tablet is used to prevent angina attacks ( chest pain ). Feeling sick (nausea). : Isosorbidmononitrat (isosorbid-5-mononitrat) 30 mg, resp. Angina. Relays have been the traditional building blocks of control since the 1950s. hot flashes, dry mouth, diarrhea, or. Imgur is the easiest way to discover and enjoy the magic of the Internet. Automated applications rely on a variety of controllers, relays, sensors, timers and modules to start, maintain, adjust and stop machinery and other components. , M. However, there is a chance that Viagra and exercise can cause your blood pressure to drop too low. 8 2. 35 59. Enclosure Style: Plug-in. Macromatic intrinsically safe relay, 35mm DIN rail mount, finger-safe, Discrete Input: 4-point, 10 VDC input voltage, 102-132 VAC or 10-125 VDC coil voltage, Discrete Output: 4-point, relay, 4PST, 5A contact rating, (4) N. 994071, til 6. A combination of alcohol and Imdur leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death. IMDUR Pill - white oval, 9mm. With input voltage applied, the V LED will be ON (GREEN) to indicate power is applied. Satisfaction. *. A client with osteoarthritis receives a. The pain of angina is usually brought on by exercise or stress. The following side effects may happen with this medicine: Headaches. It is important to discuss sexual health with your doctor. Imdur may also be used for purposes not listed in this medication guide. 1. In men without cardiovascular disease, erectile dysfunction (ED) pills are safe. PharmaPassport. com, a global distributor of electronics components. On this page about Imdur Durules you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government. arm, back, or jaw pain. Rarely, 240 mg may be required. ₹ 52. Walgreens. Imdur Overview. Normally, cardiac structures function continuously, acting as a large pump. After several days, the dosage may be increased to 120 mg (given as a single 120 mg tablet or as two 60 mg tablets) once daily. Thus, if you are on a typical dosage for Ranexa (i. com. Like other organic nitrates, isosorbide. 3. D) Request that family. I am experiencing fatigue and muscle pain, in the calves of my legs, and my shoulders. This is caused by too little blood and oxygen getting to the heart. vautomationdirectè . If it keeps up. Erectile Dysfunction (continued) Erectile Dysfunction Ver3. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. Davis PT Collection is a subscription-based resource from McGraw Hill that features trusted content from the. Approval date: June 3, 2011. Study with Quizlet and memorize flashcards containing terms like Which instruction should be included in the discharge teaching for a patient with a transdermal nitroglycerin (Nitro-Dur) patch?, The patient states to the nurse, "My friend said nitroglycerin relieves angina pain by reducing preload. 1. 60 mg once daily, may be increased to 120 mg once daily. 2. com. Side effects of Isordil that are different from Imdur include weakness and skin changes such. This medicine may be used for other purposes; ask your health care. Again, all you need to do is drag and drop images or choose files from your desktop. Choose Generic substitutes to Save up to 50% off. severe or prolonged headache. Part #: ISDUR4 / RS Stock #: 71556973 Image may be a representation. Doctoral Degree. Alprostadil intraurethral (MUSE) therapy involves4 the incidence reduces rapidly as treatment continues. The price of 30 tablets of Imdur (60 mg) averages around $130, which works out to approximately $4. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). 25 mg. Active Substances ISOSORBIDE MONONITRATE. The normal dose of isosorbide mononitrate is. 69 Long term (current) use of other immunomodulators and immunosuppressants. It is created by eHealthMe based on reports from the FDA, and is updated regularly. ISDUR4. 1 Caja, 20 Tabletas, 60 mg. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc. Comments: Optimal dosing frequency will vary depending on the individual patient, dose amount, and regimen. 36 60. Side Effects of Imdur are Headache, Dizziness. Side Effects. Hypotension (4%) with symptoms such as dizziness and nausea have been reported. Precautions. When Viagra is combined with most blood. com. Avoid tolerance by allowing at least 12 drug free hours a. Isosorbide mononitrate and dinitrate are types of heart medicine called nitrates. Product Details. 7 kg (107. I'm currently taking Coreg 3. KI. This medicine is only used to prevent or lower the number of chest pain attacks. This medicine falls under the category of drugs called nitrates. 02 102. This medicine works by relaxing the blood vessels, thus improving blood flow to the heart and. 5 to 5 milligrams (mg) about 15 minutes before expected physical or emotional stress. Standard Price 1 $473. Tiredness, drowsiness, feeling weak. Isosorbide dinitrate is in the class of drugs called nitrates, and it is used for treating and preventing angina or heart pain. Information last revised July 2023. Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). 55% of reviewers reported a positive effect, while 35% reported a negative effect. Still in wide use for simple control or power conversion, styles include electro-mechanical general or special purpose relays such as high power or hazardous location styles, as well as solid-state relays. ISOSORBIDE MONONITRATE (eye soe SOR bide mon oh NYE trate) prevents chest pain (angina). Study with Quizlet and memorize flashcards containing terms like Which medication is most likely to cause headache? Select one: Benzaclin Cipro Imdur Multaq, Mr. 56 ₹ 60. title: isdur4Z79. Do not use it to treat sudden chest pain. ISDUR4 has a 2-position DIP-switch that enables the selection of configurations that apply to all four channels. The phase IV clinical study analyzes which people take Imdur and have Weight loss. Created for people with ongoing healthcare needs but benefits everyone. 80/day. Data sources include Micromedex (updated 5 Nov 2023), Cerner Multum™. ₹37. Note that the ISP Series is. DIP Switch Settings Standard Logic. Medscape - Indication-specific dosing for Dilatrate-SR, Isordil (isosorbide dinitrate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. It causes reduction of preload and afterload and redistributes coronary flow to ischemic regions. 20 per day depending upon your dose and where you purchase it. Only 2-3% of patients withdrew during clinical trials due to this adverse effect. ISDUR4 has a two-position DIP-switch that enables the selection of configurations that apply to all channels. The pain is severe and crushing and it is characterized by feeling. Isosorbide Dinitrate (ISDN) is an intermediate acting nitrate approved for prevention of angina pectoris. Víkkun bláæða veldur því að blóðflæði til hjartans minnkar en þá dregur úr álagi á hjartað og súrefnisþörf hjartavöðvans. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. $ 27. Function: 4 CHANNEL - Selected operating configuration applied to all channels. 9. See specs for product details. Imdur® (IMD) is a sustained-release isosorbide 5-mononitrate preparation for the treatment of chronic stable angina pectoris. S. Although not all of these side effects may occur, if they do occur they may need medical attention. Generic Name: isosorbide nitrates , isosorbide dinitrate , isosorbide mononitrate. 60 mg once daily, may be increased to 120 mg once daily. 4 out of 10 from a total of 21 ratings on Drugs. Prices start at $17. Amlodipine is used to treat the following conditions: Angina. ISDUM4 has an 8-position DIP-switch for selecting configurations that apply independently to each channel. Agregar a interacciones medicamentosas. It relaxes and dilates the coronary arteries to supply an ample amount of blood/oxygen. (Form A): 3A resistive @ 125VAC @ 60°C [140°F] 30VDC resistive, Pilot Duty. These relays mount on 35mm DIN rail or can be panel mounted. Electro-Mechanical Relays. We create products for a range of applications, including residential, commercial, municipal, industrial and agricultural. PDE5 inhibitors block the PDE5 enzyme to prevent it from working. 64 Long term (current) use of myelosuppressive agent. It is important to assess blood pressure before administering. S. Imdur works by dilating the blood vessels and thereby facilitates the heart’s work in case of angina in the heart. Imdur Tablets 60mg - Patient Information Leaflet (PIL) by TopRidge Pharma Ltd. +47 9416 1078. Produce vasodilation. You may have headaches when you start taking Imdur. difficulty having an orgasm. Both Imdur and Nitrolingual may interact with calcium channel blockers and erectile dysfunction medications. D. Know the uses, side effects, composition, precautions and more about Imdur 30 mg Tablet 30's. une constipation; une diarrhée; une douleur abdominale; des étourdissements ou une sensation de tête légère suivant le passage de la station couchée ou assise à la station debout; des gaz; des maux de tête. Family: INTRINSICALLY SAFE RELAY. Generic Isordil (isosorbide dinitrate), available in packs starting at 50 tablets up to several hundred, can start as low as $. Manage your electrical processes and protect your equipment with reliable and cost-effective relays and industrial controls. ISDUR4. The recommended starting dose of isosorbide mononitrate is 5 to 10 mg of immediate release tablets twice daily. 17 4. Condition. Generic Isordil (isosorbide dinitrate), available in packs starting at 50 tablets up to several hundred, can start as low as $. isosorbide mononitrate. In smooth muscle, nitric oxide activates guanylate cyclase which increases guanosine 3’5’ monophosphate (cGMP) leading to dephosphorylation of myosin light chains and smooth muscle relaxation. 50 mg. 2. Apollo Pharmacy Pulse Oximeter PI, 1 Count. ©2022 NPS MedicineWise. , 2019. dimensions do not imply tolerance. The most common sexual problem in men is erectile dysfunction (ED). Although many have looked, there has been no clear evidence that Viagra is associated with increased rate of heart attacks or cardiovascular events. Number of Inputs 4. Adult: 25-50 mg/day orally initially; may be increased to 100 mg/day orally. Imdur tablet 60 mg is used in the management of angina (chest pain), heart failure, hypertension, and myocardial infarction. Imdur is used as a preventive treatment for angina in the heart ( angina pectoris ). Isosorbide mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins. A. Imdur Alternatives Compared. This medicine is only used to prevent or lower the number of chest pain attacks.